RESECTION OF HEPATIC METASTASES OF COLORECTAL CANCER

要旨

Among 402 patients with colorectal cancer treated surgically during the recent 6 years, 37 (9.2%) developed hepatic metastases were clinically studied. Twenty-nine patients had synchronous hepatic metastasis (7.2%), and 11 of them underwent hepatectomy. The 3-year survival rate for these 11 patients was 43%, which was higher than the rate (13%) for those who did not undergo hepatectomy. Eight patients had metachronous hepatic metastasis (2.0%), and 7 of them underwent hepatectomy. The 5-year survival rate for these 7 patients was 80%, which was higher than that (0%) for the non-receiver. In posthepatectomy patients with synchronous hepatic metastasis, recurrence in the remnant liver was as high as 75%, but no recurrence was found in 3 patients undergoing one-shot intraarterial chemotherapy postoperatively. Patients with hepatic metastasis from colorectal cancer receiving hepatectomy had better prognosis than that of non-receivers. From these findings hepatectomy should be recommended for the treatment of hepatic metastasis even in H2 cases if complete resection of the metastatic lesion is possible. It is also indicated that one-shot intraarterial chemotherapy is useful in preventing recurrence in the remnant liver in cases of synchronous hepatic metastasis where the incidence of such recurrence is high.

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